Dr. Mesmer is now doing research at a local university, conducting experiments in mind control, using advanced technology. His cute lab assistant has had her mind replaced with his patented "Lab Girl" program. They take a break from research, and she fulfills his every sexual desire without question, each act being triggered by a written command, emblazoned across a large, stuffed Valentine heart.

J.I.S.M. girl Arachnia has the powers of a spider. So Dr. Steele sends over his minion The X-terminator, who quickly subdues her with an industrial strength bug spray. It puts her under his power, and she becomes his moll, fulfilling his every command, starting with a crime spree and ending with hot sex back at the lair.

An unscrupulous MC porn director (is there any other kind?) places a fake audition notice in a Tinsel Town trade paper in an attempt to lure unsuspecting actresses into his mesmerizing clutches. Once under his spell he uses them as free labor in his adult productions.

Dr. Metallus sends a busty cleaning cyborg to Dr. Mesmer in repayment for the latter giving him a lab girl. While the beautiful robot cleans his house, the doctor calls Lacie, the cute, blond president of the I Eta Pi sorority. He invites her over to take advantage of the cyborg, while he watches. Turned on by what he sees, Mesmer mesmerizes the lesbian into liking men and has sex with both beautiful females.

A lusty lesbian, living in a house once rented by a mad scientist, is trying to seduce her platonic friend. She has little success until a disembodied brain, hidden in the garage by the former tenant, sends telepathic emanations, encouraging the straight girl to have sex with her. Then the brain's former body, hidden in the tool shed, breaks in on them and gives the straight girl what she really wants.

Dr. Mesmer's colleague, Dr. Metallus, offers a trade: one of Mesmer's "lab girls" in exchange for one of his own cleaning cyborgs. Mesmer hooks Maya up to the "Halo of Forgetfullness" to install the program, but leaves her on too long. She's reduced to a primitive state and is always sexually aroused. It takes Metallus and Mesmer to satisfy her lust.

Dr. Steele, using his power over metal, subdues Cobalt Chick, the J.I.S.M. Girls' super strong 18 year old mascot. He brings her back to his headquarters, where he and his sidekick, Aluminum Foil Guy, teach her about hot supervillain love. Wait til you see the ass on Cobalt Chick!

Gianna is unlucky in love. She visits a gypsy fortune teller to predict if she will ever find true romance. He mesmerizes her with his crystal balls, and makes her his love slave. Maybe that's not the kind of love she was looking for, but her fortune teller doesn't care. Porn legend Gianna Michaels and her humungous hooters star!